With the No$Gba v2.3 you can play commercial Nintendo DS games on your PC. For now only selected games are compatible and to get them working you need to encrypt the ROMS first. There also a few crucial features missing like WLAN and the most important of all sound. Also what fun is playing Mario using the keyboard compared to the controller.

Download No$Gba v2.3 now
Check out the compatibility list here.